First-pass-effect — [fö̱rßtpá̱ßefäkt; engl. first = erster, engl. pass = Zugang, Durchgang u. engl. effect = Effekt] m; , s: teilweise oder vollständige Verminderung der Bioverfügbarkeit eines peroral verabreichten Arzneimittels durch metabolische Veränderungen … Das Wörterbuch medizinischer Fachausdrücke
First pass effect — The first pass effect (also known as first pass metabolism or presystemic metabolism) is a phenomenon of drug metabolism whereby the concentration of a drug is greatly reduced before it reaches the systemic circulation.After a drug is swallowed,… … Wikipedia
First-Pass-Effect — First Pass Ef|fect [ fə:st pɑ:s|i fɛkt] der; , s <zu engl. first »Erster«, pass »Zugang, Durchgang« u. effect »Wirkung«> teilweise od. vollständige Verminderung der Bioverfügbarkeit eines durch den Mund verabreichten Arzneimittels durch… … Das große Fremdwörterbuch
Pass — Contents 1 Admission and permission 2 Acronyms 3 Transport 4 … Wikipedia
effect — The result or consequence of an action. [L. efficio, pp. effectus, to accomplish, fr. facio, to do] abscopal e. a reaction produced following irradiation but occurring outside the zone of actual radiation absorption. additive e. an e. wherein two … Medical dictionary
First Amendment to the United States Constitution — First Amendment redirects here. For other uses, see First Amendment (disambiguation). United States of America This a … Wikipedia
First Battle of El Alamein — Part of Western Desert Campaign … Wikipedia
First Battle of Bull Run — (First Manassas) Part of the American Civil War Fi … Wikipedia
First English Civil War — The First English Civil War (1642–1646) was the first of three wars known as the English Civil War (or Wars ). The English Civil War was a series of armed conflicts and political machinations which took place between Parliamentarians and… … Wikipedia
First Nations — This article is about the indigenous peoples of Canada. For other indigenous peoples, see Indigenous peoples by geographic regions. First Nations … Wikipedia
First Transcontinental Railroad — This article refers to a railroad built in the United States between Omaha and Sacramento, completed in 1869. For other transcontinental railroads see transcontinental railroad. At the ceremony for the driving of the Last Spike at Promontory… … Wikipedia